产品货号：
Z19035
中文名称：
Junctophilin-4/JPH4抗体
英文名称：
Anti-Junctophilin-4/JPH4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Junctophilin-4/JPH4 Antibody |
| 指标别名 | JP4;JPHL1;KIAA1831;Junctophilin-4;Junctophilin-like 1 protein;JP-4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | JPH4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JPH4 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human JPH4.The immunogen is located within amino acids 530 - 580 of JPH4. |
| 计算分子量 | 66kDa |
| 成分 | JPH4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JPH4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels.Junctophilins (JPs) are important components of the junctional complexes.JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM.Four JPs have been identified as tissue-specific subtypes derived from different genes:JPH1 is expressed in skeletal muscle,JPH2 is detected throughout all muscle cell types,and JPH3 and JPH4 are predominantly expressed in the brain.In the CNS,both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons.Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions. |
| Uniprot ID | Q96JJ6 |
| 基因名全称 | Junctophilin 4 |
| 蛋白名全称 | Junctophilin 4 |
| 推荐稀释比 | JPH4 antibody can be used for detection of JPH4 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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